World supplier of antibodies, antigens and kits since 2007
2019-nCoV & Monkeypox
Biotinylated Human ACE-2 (C-Avi-6His)
Price on request
Quantity
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Specificty Sensitivity
Specificity/SensitivityHuman
Product Information
PurityGreater than 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation：Affinity purification chromatography.
FormName:Biotinylated Human ACE-2 (C-Avi-6His)
Other NamesAngiotensin-Converting Enzyme2; ACE-Related Carboxy peptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
Storage/StabilityStore at < -20°C, stable for 6 months after receipt.
Immunogen, calibrator or standard.
BackgroundAngiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Immobilized 2019-nCoV S1 Protein-Fc (Cat# E42020T3) at 2μg/ml (100 μl/ well) can bind Biotinylated Human ACE-2-Avi-His (Cat# E21-Y51-1). The ED50 of Biotinylated Human ACE-2-Avi-His (Cat# E21-Y51-1) is 0.17 ug/ml.
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