Catalog Number:
E21-R06Amount:
10ugPrice:
225$Altername:
Tumor necrosis factor ligand superfamily member 11;Tnfsf11;Osteoclast differentiation factor;ODF;Osteoprotegerin ligand;OPGL;Receptor activator of nuclear factor kappa-B ligand;RANKL;TNF-related activation-induced cytokine;TRANCE;CD254Storage/Stability:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Background:
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.Species:
MouseReconstitution:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.Endotoxin:
Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.Purity:
Greater than 95% as determined by reducing SDS-PAGE.Description:
Recombinant Mouse TNF ligand superfamily member 11 is produced by our E.coli expression system and the target gene encoding Gln137-Asp316 is expressed.Product State:
LyophilizedShip Description:
The product is shipped at ambient temperature.Formulation:
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Expression system:
E.coli