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Cell Signal Transduction Research Antibodies

BMP-6 Polyclonal Antibody

E20-75655Cite ID: EN0055788DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight57226Da
Protein NameBone morphogenetic protein 6
Human Gene Id654
Human Swiss Prot NoP22004
Mouse Gene Id12161
Mouse Swiss Prot NoP20722
Rat Gene Id25644
Rat Swiss Prot NoQ04906
SpecificityBMP-6 Polyclonal Antibody detects endogenous levels of BMP-6 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBMP6; VGR; Bone morphogenetic protein 6; BMP-6; VG-1-related protein; VG-1-R; VGR-1
Observed Band(KD)60
Functionfunction:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 6 entry,similarity:Belongs to the TGF-beta family.,subunit:Interacts with SOSTDC1.,
Subcellular Locationextracellular region,extracellular space,cytoplasm,membrane-bounded vesicle,
ExpressionBone,PCR rescued clones,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BMP6. AA range:341-390
Gene NameBMP6
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundbone morphogenetic protein 6(BMP6) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],

Conjugated Antibody

This product is also available conjugated. Format: E20-75655-Conjugate. Price: $485 / Size: 100μl.

E20-75655-FITC$485 / 100μlE20-75655-Biotin$485 / 100μlE20-75655-HRP$485 / 100μlE20-75655-AP$485 / 100μlE20-75655-AF350$485 / 100μlE20-75655-AF405M$485 / 100μlE20-75655-AF488$485 / 100μlE20-75655-AF514$485 / 100μlE20-75655-AF532$485 / 100μlE20-75655-AF555$485 / 100μlE20-75655-AF568$485 / 100μlE20-75655-AF405S$485 / 100μlE20-75655-AF405L$485 / 100μlE20-75655-AF546$485 / 100μlE20-75655-AF594$485 / 100μlE20-75655-AF610$485 / 100μlE20-75655-AF635$485 / 100μlE20-75655-AF647$485 / 100μlE20-75655-AF680$485 / 100μlE20-75655-AF700$485 / 100μlE20-75655-AF750$485 / 100μlE20-75655-AF790$485 / 100μlE20-75655-APC$485 / 100μlE20-75655-PE$485 / 100μlE20-75655-Cy3$485 / 100μlE20-75655-Cy5$485 / 100μlE20-75655-Cy5.5$485 / 100μlE20-75655-Cy7$485 / 100μlE20-75655-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.