Product Information
Molecular Weight46966Da
Protein NameGrowth/differentiation factor 7
Human Gene Id151449
Human Swiss Prot NoQ7Z4P5
Mouse Gene Id238057
Mouse Swiss Prot NoP43029
SpecificityGDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGDF7; Growth/differentiation factor 7; GDF-7
Observed Band(KD)47
Functionfunction:May play an active role in the motor area of the primate neocortex.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
Subcellular Locationextracellular region,extracellular space,
ExpressionTestis,
Backgroundgrowth differentiation factor 7(GDF7) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],