Lefty Polyclonal Antibody

Name: Lefty Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75647
Price: 225 USD
Availability: InStock

E20-75647Cite ID: EN0055780Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight40880/40920Da

Protein NameLeft-right determination factor 1/Left-right determination factor 2

Human Gene Id10637/7044

Human Swiss Prot NoO75610/O00292

Mouse Gene Id13590/320202

SpecificityLefty Polyclonal Antibody detects endogenous levels of Lefty protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameLEFTY1; LEFTB; LEFTYB; Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B; LEFTY2; EBAF; LEFTA; LEFTYA; TGFB4; PSEC0024; Left-right determination factor 2; Endometrial bleeding-associated factor; Left-right determination factor A; Protein lefty-2; Protein lefty-A; Transforming growth factor beta-4; TGF-beta-4

Observed Band(KD)40

Functionfunction:Required for left-right axis determination as a regulator of LEFTY2 and NODAL.,PTM:The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.,similarity:Belongs to the TGF-beta family.,

Subcellular Locationextracellular space,

ExpressionColon,Pancreas,Spleen,Teratocarcinoma,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2. AA range:301-350

Gene NameLEFTY1/LEFTY2

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundleft-right determination factor 1(LEFTY1) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75647-Conjugate. Price: $485 / Size: 100μl.

E20-75647-FITC$485 / 100μlE20-75647-Biotin$485 / 100μlE20-75647-HRP$485 / 100μlE20-75647-AP$485 / 100μlE20-75647-AF350$485 / 100μlE20-75647-AF405M$485 / 100μlE20-75647-AF488$485 / 100μlE20-75647-AF514$485 / 100μlE20-75647-AF532$485 / 100μlE20-75647-AF555$485 / 100μlE20-75647-AF568$485 / 100μlE20-75647-AF405S$485 / 100μlE20-75647-AF405L$485 / 100μlE20-75647-AF546$485 / 100μlE20-75647-AF594$485 / 100μlE20-75647-AF610$485 / 100μlE20-75647-AF635$485 / 100μlE20-75647-AF647$485 / 100μlE20-75647-AF680$485 / 100μlE20-75647-AF700$485 / 100μlE20-75647-AF750$485 / 100μlE20-75647-AF790$485 / 100μlE20-75647-APC$485 / 100μlE20-75647-PE$485 / 100μlE20-75647-Cy3$485 / 100μlE20-75647-Cy5$485 / 100μlE20-75647-Cy5.5$485 / 100μlE20-75647-Cy7$485 / 100μlE20-75647-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.