Product Information
Molecular Weight41387Da
Protein NameGrowth/differentiation factor 3
Human Gene Id9573
Human Swiss Prot NoQ9NR23
Mouse Gene Id14562
Mouse Swiss Prot NoQ07104
SpecificityGDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGDF3; Growth/differentiation factor 3; GDF-3
Observed Band(KD)41
Functiononline information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,
Subcellular Locationextracellular space,cytoplasm,
ExpressionKidney,
Backgroundgrowth differentiation factor 3(GDF3) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],