World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Amphiregulin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight27895Da
Protein NameAmphiregulin
Human Gene Id374/727738
Human Swiss Prot NoP15514
Mouse Gene Id11839
Mouse Swiss Prot NoP31955
Rat Gene Id29183
Rat Swiss Prot NoP24338
SpecificityAmphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameAREG; SDGF; AREGB; Amphiregulin; AR; Colorectum cell-derived growth factor; CRDGF
Observed Band(KD)29
Functionfunction:Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.,induction:By phorbol 12-myristate 13-acetate (PMA).,miscellaneous:AR is a protein containing cysteines in disulfide linkage(s) that are essential for its biological activity. AR may contain oligosaccharides and/or lipid moieties that are not obligatory for the biological activity.,similarity:Belongs to the amphiregulin family.,similarity:Contains 1 EGF-like domain.,subunit:The immature precursor interacts with CNIH.,
Subcellular LocationGolgi membrane,extracellular space,nucleus,endoplasmic reticulum membrane,cell surface,ER to Golgi transport vesicle membrane,integral component of membrane,endoplasmic reticulum-Golgi intermediate compartment membrane,
ExpressionBrain,Pooled,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140
Gene NameAREG/AREGB
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundamphiregulin(AREG) Homo sapiens The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-75644-Conjugate. Price: $485 / Size: 100μl.
E20-75644-FITC$485 / 100μlE20-75644-Biotin$485 / 100μlE20-75644-HRP$485 / 100μlE20-75644-AP$485 / 100μlE20-75644-AF350$485 / 100μlE20-75644-AF405M$485 / 100μlE20-75644-AF488$485 / 100μlE20-75644-AF514$485 / 100μlE20-75644-AF532$485 / 100μlE20-75644-AF555$485 / 100μlE20-75644-AF568$485 / 100μlE20-75644-AF405S$485 / 100μlE20-75644-AF405L$485 / 100μlE20-75644-AF546$485 / 100μlE20-75644-AF594$485 / 100μlE20-75644-AF610$485 / 100μlE20-75644-AF635$485 / 100μlE20-75644-AF647$485 / 100μlE20-75644-AF680$485 / 100μlE20-75644-AF700$485 / 100μlE20-75644-AF750$485 / 100μlE20-75644-AF790$485 / 100μlE20-75644-APC$485 / 100μlE20-75644-PE$485 / 100μlE20-75644-Cy3$485 / 100μlE20-75644-Cy5$485 / 100μlE20-75644-Cy5.5$485 / 100μlE20-75644-Cy7$485 / 100μlE20-75644-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits