World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
Probetacellulin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight19746Da
Protein NameProbetacellulin
Human Gene Id685
Human Swiss Prot NoP35070
Mouse Gene Id12223
Mouse Swiss Prot NoQ05928
SpecificityProbetacellulin Polyclonal Antibody detects endogenous levels of Probetacellulin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBTC; Probetacellulin
Observed Band(KD)20
Functiondisease:Betacellulin from beta cells could play a role in the vascular complications associated with diabetes.,function:Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.,similarity:Contains 1 EGF-like domain.,subunit:Monomer.,tissue specificity:Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.,
Subcellular Locationextracellular region,extracellular space,intracellular,plasma membrane,integral component of membrane,
ExpressionMammary gland,Ovary,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BTC. AA range:21-70
Gene NameBTC
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundbetacellulin(BTC) Homo sapiens This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients. [provided by RefSeq, Nov 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75642-Conjugate. Price: $485 / Size: 100μl.
E20-75642-FITC$485 / 100μlE20-75642-Biotin$485 / 100μlE20-75642-HRP$485 / 100μlE20-75642-AP$485 / 100μlE20-75642-AF350$485 / 100μlE20-75642-AF405M$485 / 100μlE20-75642-AF488$485 / 100μlE20-75642-AF514$485 / 100μlE20-75642-AF532$485 / 100μlE20-75642-AF555$485 / 100μlE20-75642-AF568$485 / 100μlE20-75642-AF405S$485 / 100μlE20-75642-AF405L$485 / 100μlE20-75642-AF546$485 / 100μlE20-75642-AF594$485 / 100μlE20-75642-AF610$485 / 100μlE20-75642-AF635$485 / 100μlE20-75642-AF647$485 / 100μlE20-75642-AF680$485 / 100μlE20-75642-AF700$485 / 100μlE20-75642-AF750$485 / 100μlE20-75642-AF790$485 / 100μlE20-75642-APC$485 / 100μlE20-75642-PE$485 / 100μlE20-75642-Cy3$485 / 100μlE20-75642-Cy5$485 / 100μlE20-75642-Cy5.5$485 / 100μlE20-75642-Cy7$485 / 100μlE20-75642-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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