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Cell Signal Transduction Research Antibodies
CD192 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight41915Da
Protein NameC-C chemokine receptor type 2
Human Gene Id729230
Human Swiss Prot NoP41597
Mouse Gene Id12772
Mouse Swiss Prot NoP51683
Rat Gene Id60463
Rat Swiss Prot NoO55193
SpecificityCD192 Polyclonal Antibody detects endogenous levels of CD192 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCCR2; CMKBR2; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD192
Observed Band(KD)42
Functionfunction:Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.,online information:CC chemokine receptors entry,polymorphism:Variations in CCR2 are associated with relative resistance to immunodeficiency virus type 1 (resistance to HIV-1) [MIM:609423].,PTM:N-glycosylated.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Binds to HIV-1 Tat.,
Subcellular Locationcytoplasm,cytosol,plasma membrane,integral component of plasma membrane,integral component of membrane,dendrite,neuronal cell body,perikaryon,perinuclear region of cytoplasm,
ExpressionG-protein coupled receptors,Thymus,Trachea,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR2. AA range:1-50
Gene NameCCR2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundC-C motif chemokine receptor 2(CCR2) Homo sapiens This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75635-Conjugate. Price: $485 / Size: 100μl.
E20-75635-FITC$485 / 100μlE20-75635-Biotin$485 / 100μlE20-75635-HRP$485 / 100μlE20-75635-AP$485 / 100μlE20-75635-AF350$485 / 100μlE20-75635-AF405M$485 / 100μlE20-75635-AF488$485 / 100μlE20-75635-AF514$485 / 100μlE20-75635-AF532$485 / 100μlE20-75635-AF555$485 / 100μlE20-75635-AF568$485 / 100μlE20-75635-AF405S$485 / 100μlE20-75635-AF405L$485 / 100μlE20-75635-AF546$485 / 100μlE20-75635-AF594$485 / 100μlE20-75635-AF610$485 / 100μlE20-75635-AF635$485 / 100μlE20-75635-AF647$485 / 100μlE20-75635-AF680$485 / 100μlE20-75635-AF700$485 / 100μlE20-75635-AF750$485 / 100μlE20-75635-AF790$485 / 100μlE20-75635-APC$485 / 100μlE20-75635-PE$485 / 100μlE20-75635-Cy3$485 / 100μlE20-75635-Cy5$485 / 100μlE20-75635-Cy5.5$485 / 100μlE20-75635-Cy7$485 / 100μlE20-75635-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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