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Cell Signal Transduction Research Antibodies

NKp30 Polyclonal Antibody

E20-75631Cite ID: EN0055764DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight21593Da
Protein NameNatural cytotoxicity triggering receptor 3
Human Gene Id259197
Human Swiss Prot NoO14931
Rat Swiss Prot NoQ8CFD9
SpecificityNKp30 Polyclonal Antibody detects endogenous levels of NKp30 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNCR3; 1C7; LY117; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD337
Observed Band(KD)21
Functionfunction:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,polymorphism:A genetic variation in NCR3 is associated with mild malaria suceptibility [MIM:609148].,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Interacts with CD3Z.,tissue specificity:Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.,
Subcellular Locationplasma membrane,integral component of plasma membrane,cell-cell adherens junction,
ExpressionBlood,Lymphoid,Peripheral blood,Spleen,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human NCR3. AA range:91-140
Gene NameNCR3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundnatural cytotoxicity triggering receptor 3(NCR3) Homo sapiens The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010],

Conjugated Antibody

This product is also available conjugated. Format: E20-75631-Conjugate. Price: $485 / Size: 100μl.

E20-75631-FITC$485 / 100μlE20-75631-Biotin$485 / 100μlE20-75631-HRP$485 / 100μlE20-75631-AP$485 / 100μlE20-75631-AF350$485 / 100μlE20-75631-AF405M$485 / 100μlE20-75631-AF488$485 / 100μlE20-75631-AF514$485 / 100μlE20-75631-AF532$485 / 100μlE20-75631-AF555$485 / 100μlE20-75631-AF568$485 / 100μlE20-75631-AF405S$485 / 100μlE20-75631-AF405L$485 / 100μlE20-75631-AF546$485 / 100μlE20-75631-AF594$485 / 100μlE20-75631-AF610$485 / 100μlE20-75631-AF635$485 / 100μlE20-75631-AF647$485 / 100μlE20-75631-AF680$485 / 100μlE20-75631-AF700$485 / 100μlE20-75631-AF750$485 / 100μlE20-75631-AF790$485 / 100μlE20-75631-APC$485 / 100μlE20-75631-PE$485 / 100μlE20-75631-Cy3$485 / 100μlE20-75631-Cy5$485 / 100μlE20-75631-Cy5.5$485 / 100μlE20-75631-Cy7$485 / 100μlE20-75631-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.