World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
IL-10Rα Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight62904Da
Protein NameInterleukin-10 receptor subunit alpha
Human Gene Id3587
Human Swiss Prot NoQ13651
Mouse Gene Id16154
Mouse Swiss Prot NoQ61727
SpecificityIL-10Rα Polyclonal Antibody detects endogenous levels of IL-10Rα protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameIL10RA; IL10R; Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210
Observed Band(KD)63
Functionfunction:Receptor for IL10; binds IL10 with a high affinity.,similarity:Belongs to the type II cytokine receptor family.,tissue specificity:Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.,
Subcellular Locationplasma membrane,integral component of membrane,
ExpressionBlood,Lymphoma,Spleen,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL10RA. AA range:151-200
Gene NameIL10RA
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundinterleukin 10 receptor subunit alpha(IL10RA) Homo sapiens The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75630-Conjugate. Price: $485 / Size: 100μl.
E20-75630-FITC$485 / 100μlE20-75630-Biotin$485 / 100μlE20-75630-HRP$485 / 100μlE20-75630-AP$485 / 100μlE20-75630-AF350$485 / 100μlE20-75630-AF405M$485 / 100μlE20-75630-AF488$485 / 100μlE20-75630-AF514$485 / 100μlE20-75630-AF532$485 / 100μlE20-75630-AF555$485 / 100μlE20-75630-AF568$485 / 100μlE20-75630-AF405S$485 / 100μlE20-75630-AF405L$485 / 100μlE20-75630-AF546$485 / 100μlE20-75630-AF594$485 / 100μlE20-75630-AF610$485 / 100μlE20-75630-AF635$485 / 100μlE20-75630-AF647$485 / 100μlE20-75630-AF680$485 / 100μlE20-75630-AF700$485 / 100μlE20-75630-AF750$485 / 100μlE20-75630-AF790$485 / 100μlE20-75630-APC$485 / 100μlE20-75630-PE$485 / 100μlE20-75630-Cy3$485 / 100μlE20-75630-Cy5$485 / 100μlE20-75630-Cy5.5$485 / 100μlE20-75630-Cy7$485 / 100μlE20-75630-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits