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Cell Signal Transduction Research Antibodies
EMR2 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight90472Da
Protein NameEGF-like module-containing mucin-like hormone receptor-like 2
Human Gene Id30817
Human Swiss Prot NoQ9UHX3
SpecificityEMR2 Polyclonal Antibody detects endogenous levels of EMR2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameEMR2; EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD312
Observed Band(KD)72
Functionalternative products:A number of isoforms are produced. A number of isoforms consisting of various number of EGF-like domains seems to exist. A soluble form due to a frameshift which introduced a stop codon immediately before the first TM domain is also detected,domain:Binding to chondroitin sulfate is mediated by the fourth EGF domain.,domain:The GPS domain is necessary, but not sufficient for receptor cleavage, which require the entire extracellular stalk.,function:Receptor probably involved in cell attachment.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 5 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembr
Subcellular Locationplasma membrane,membrane,integral component of membrane,leading edge membrane,ruffle membrane,
ExpressionKidney,Spleen,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human EMR2. AA range:491-540
Gene NameEMR2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundadhesion G protein-coupled receptor E2(ADGRE2) Homo sapiens This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-75625-Conjugate. Price: $485 / Size: 100μl.
E20-75625-FITC$485 / 100μlE20-75625-Biotin$485 / 100μlE20-75625-HRP$485 / 100μlE20-75625-AP$485 / 100μlE20-75625-AF350$485 / 100μlE20-75625-AF405M$485 / 100μlE20-75625-AF488$485 / 100μlE20-75625-AF514$485 / 100μlE20-75625-AF532$485 / 100μlE20-75625-AF555$485 / 100μlE20-75625-AF568$485 / 100μlE20-75625-AF405S$485 / 100μlE20-75625-AF405L$485 / 100μlE20-75625-AF546$485 / 100μlE20-75625-AF594$485 / 100μlE20-75625-AF610$485 / 100μlE20-75625-AF635$485 / 100μlE20-75625-AF647$485 / 100μlE20-75625-AF680$485 / 100μlE20-75625-AF700$485 / 100μlE20-75625-AF750$485 / 100μlE20-75625-AF790$485 / 100μlE20-75625-APC$485 / 100μlE20-75625-PE$485 / 100μlE20-75625-Cy3$485 / 100μlE20-75625-Cy5$485 / 100μlE20-75625-Cy5.5$485 / 100μlE20-75625-Cy7$485 / 100μlE20-75625-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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