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Cell Signal Transduction Research Antibodies

CD298 Polyclonal Antibody

E20-75623Cite ID: EN0055756DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight31513Da
Protein NameSodium/potassium-transporting ATPase subunit beta-3
Human Gene Id483
Human Swiss Prot NoP54709
Mouse Gene Id11933
Mouse Swiss Prot NoP97370
Rat Gene Id25390
Rat Swiss Prot NoQ63377
SpecificityCD298 Polyclonal Antibody detects endogenous levels of CD298 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameATP1B3; Sodium/potassium-transporting ATPase subunit beta-3; Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3; CD298
Observed Band(KD)36
Functionfunction:This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.,similarity:Belongs to the X(+)/potassium ATPases subunit beta family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma.,
Subcellular Locationplasma membrane,sodium:potassium-exchanging ATPase complex,caveola,melanosome,extracellular exosome,
ExpressionLung,Placenta,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human ATP1B3. AA range:222-271
Gene NameATP1B3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundATPase Na+/K+ transporting subunit beta 3(ATP1B3) Homo sapiens The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subun

Conjugated Antibody

This product is also available conjugated. Format: E20-75623-Conjugate. Price: $485 / Size: 100μl.

E20-75623-FITC$485 / 100μlE20-75623-Biotin$485 / 100μlE20-75623-HRP$485 / 100μlE20-75623-AP$485 / 100μlE20-75623-AF350$485 / 100μlE20-75623-AF405M$485 / 100μlE20-75623-AF488$485 / 100μlE20-75623-AF514$485 / 100μlE20-75623-AF532$485 / 100μlE20-75623-AF555$485 / 100μlE20-75623-AF568$485 / 100μlE20-75623-AF405S$485 / 100μlE20-75623-AF405L$485 / 100μlE20-75623-AF546$485 / 100μlE20-75623-AF594$485 / 100μlE20-75623-AF610$485 / 100μlE20-75623-AF635$485 / 100μlE20-75623-AF647$485 / 100μlE20-75623-AF680$485 / 100μlE20-75623-AF700$485 / 100μlE20-75623-AF750$485 / 100μlE20-75623-AF790$485 / 100μlE20-75623-APC$485 / 100μlE20-75623-PE$485 / 100μlE20-75623-Cy3$485 / 100μlE20-75623-Cy5$485 / 100μlE20-75623-Cy5.5$485 / 100μlE20-75623-Cy7$485 / 100μlE20-75623-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.