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Cell Signal Transduction Research Antibodies
CD30-L Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight26017Da
Protein NameTumor necrosis factor ligand superfamily member 8
Human Gene Id944
Human Swiss Prot NoP32971
Mouse Gene Id21949
Mouse Swiss Prot NoP32972
SpecificityCD30-L Polyclonal Antibody detects endogenous levels of CD30-L protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTNFSF8; CD30L; CD30LG; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD153
Observed Band(KD)26
Functionfunction:Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,
Subcellular Locationextracellular space,integral component of plasma membrane,integral component of membrane,
ExpressionBrain,Thymus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF8. AA range:131-180
Gene NameTNFSF8
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundtumor necrosis factor superfamily member 8(TNFSF8) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-75622-Conjugate. Price: $485 / Size: 100μl.
E20-75622-FITC$485 / 100μlE20-75622-Biotin$485 / 100μlE20-75622-HRP$485 / 100μlE20-75622-AP$485 / 100μlE20-75622-AF350$485 / 100μlE20-75622-AF405M$485 / 100μlE20-75622-AF488$485 / 100μlE20-75622-AF514$485 / 100μlE20-75622-AF532$485 / 100μlE20-75622-AF555$485 / 100μlE20-75622-AF568$485 / 100μlE20-75622-AF405S$485 / 100μlE20-75622-AF405L$485 / 100μlE20-75622-AF546$485 / 100μlE20-75622-AF594$485 / 100μlE20-75622-AF610$485 / 100μlE20-75622-AF635$485 / 100μlE20-75622-AF647$485 / 100μlE20-75622-AF680$485 / 100μlE20-75622-AF700$485 / 100μlE20-75622-AF750$485 / 100μlE20-75622-AF790$485 / 100μlE20-75622-APC$485 / 100μlE20-75622-PE$485 / 100μlE20-75622-Cy3$485 / 100μlE20-75622-Cy5$485 / 100μlE20-75622-Cy5.5$485 / 100μlE20-75622-Cy7$485 / 100μlE20-75622-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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