Product Information
Molecular Weight34481Da
Protein NameNatural cytotoxicity triggering receptor 1
Human Gene Id9437
Human Swiss Prot NoO76036
Mouse Gene Id17086
Mouse Swiss Prot NoQ8C567
Rat Gene Id117547
Rat Swiss Prot NoQ9Z0H5
SpecificityNKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNCR1; LY94; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD335
Observed Band(KD)34
Functionfunction:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,
Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,SWI/SNF complex,
ExpressionBlood,Lymphoid,
Backgroundfunction:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,