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Cell Signal Transduction Research Antibodies

Ox40L Polyclonal Antibody

E20-75620Cite ID: EN0055753DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight21050Da
Protein NameTumor necrosis factor ligand superfamily member 4
Human Gene Id7292
Human Swiss Prot NoP23510
Mouse Gene Id22164
Mouse Swiss Prot NoP43488
Rat Gene Id89814
Rat Swiss Prot NoQ9Z2P3
SpecificityOx40L Polyclonal Antibody detects endogenous levels of Ox40L protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTNFSF4; TXGP1; Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; CD252
Observed Band(KD)21
Functiondisease:Genetic variation in TNFSF4 influences susceptibility to systemic lupus erythematosus (SLE) [MIM:152700]. SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.,function:Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.,induction:By human T-cell leukemia virus type I transactivator P40-TAX.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,
Subcellular Locationextracellular space,plasma membrane,integral component of plasma membrane,cell surface,integral component of membrane,
ExpressionTestis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF4. AA range:31-80
Gene NameTNFSF4
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundtumor necrosis factor superfamily member 4(TNFSF4) Homo sapiens This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Conjugated Antibody

This product is also available conjugated. Format: E20-75620-Conjugate. Price: $485 / Size: 100μl.

E20-75620-FITC$485 / 100μlE20-75620-Biotin$485 / 100μlE20-75620-HRP$485 / 100μlE20-75620-AP$485 / 100μlE20-75620-AF350$485 / 100μlE20-75620-AF405M$485 / 100μlE20-75620-AF488$485 / 100μlE20-75620-AF514$485 / 100μlE20-75620-AF532$485 / 100μlE20-75620-AF555$485 / 100μlE20-75620-AF568$485 / 100μlE20-75620-AF405S$485 / 100μlE20-75620-AF405L$485 / 100μlE20-75620-AF546$485 / 100μlE20-75620-AF594$485 / 100μlE20-75620-AF610$485 / 100μlE20-75620-AF635$485 / 100μlE20-75620-AF647$485 / 100μlE20-75620-AF680$485 / 100μlE20-75620-AF700$485 / 100μlE20-75620-AF750$485 / 100μlE20-75620-AF790$485 / 100μlE20-75620-APC$485 / 100μlE20-75620-PE$485 / 100μlE20-75620-Cy3$485 / 100μlE20-75620-Cy5$485 / 100μlE20-75620-Cy5.5$485 / 100μlE20-75620-Cy7$485 / 100μlE20-75620-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.