Mucin 1 Polyclonal Antibody

Name: Mucin 1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75617
Price: 225 USD
Availability: InStock

E20-75617Cite ID: EN0055750Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight122072Da

Protein NameMucin-1

Human Gene Id4582

Human Swiss Prot NoP15941

Mouse Gene Id17829

Mouse Swiss Prot NoQ02496

SpecificityMucin 1 Polyclonal Antibody detects endogenous levels of Mucin 1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD227

Observed Band(KD)122

Functionalternative products:Additional isoforms seem to exist,caution:O-glycosylation sites are annotated in first sequence repeat only. Residues at similar position are probably glycosylated in all repeats. Experimental sites were determined in a synthetic peptide glycosylated in vitro (PubMed:7744025, PubMed:9597769).,caution:The N-terminal sequence has been shown (PubMed:11341784) to begin at position 24 or 28.,developmental stage:During fetal development, expressed at low levels in the colonic epithelium from 13 weeks of gestation.,function:The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.,function:The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates s

Subcellular Locationnuclear chromatin,extracellular space,cytoplasm,Golgi lumen,integral component of plasma membrane,integral component of membrane,apical plasma membrane,vesicle,extracellular exosome,

ExpressionBlood,Carcinoma,Cervix carcinoma,Lung,Mammary carcinoma,Pancreatic carcinom

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MUC1. AA range:1021-1070

Gene NameMUC1

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Backgroundmucin 1, cell surface associated(MUC1) Homo sapiens This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75617-Conjugate. Price: $485 / Size: 100μl.

E20-75617-FITC$485 / 100μlE20-75617-Biotin$485 / 100μlE20-75617-HRP$485 / 100μlE20-75617-AP$485 / 100μlE20-75617-AF350$485 / 100μlE20-75617-AF405M$485 / 100μlE20-75617-AF488$485 / 100μlE20-75617-AF514$485 / 100μlE20-75617-AF532$485 / 100μlE20-75617-AF555$485 / 100μlE20-75617-AF568$485 / 100μlE20-75617-AF405S$485 / 100μlE20-75617-AF405L$485 / 100μlE20-75617-AF546$485 / 100μlE20-75617-AF594$485 / 100μlE20-75617-AF610$485 / 100μlE20-75617-AF635$485 / 100μlE20-75617-AF647$485 / 100μlE20-75617-AF680$485 / 100μlE20-75617-AF700$485 / 100μlE20-75617-AF750$485 / 100μlE20-75617-AF790$485 / 100μlE20-75617-APC$485 / 100μlE20-75617-PE$485 / 100μlE20-75617-Cy3$485 / 100μlE20-75617-Cy5$485 / 100μlE20-75617-Cy5.5$485 / 100μlE20-75617-Cy7$485 / 100μlE20-75617-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.