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Cell Signal Transduction Research Antibodies
CD244 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight41616Da
Protein NameNatural killer cell receptor 2B4
Human Gene Id51744
Human Swiss Prot NoQ9BZW8
Mouse Swiss Prot NoQ07763
SpecificityCD244 Polyclonal Antibody detects endogenous levels of CD244 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD244; 2B4; Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; CD244
Observed Band(KD)42
Functionfunction:Modulate other receptor-ligand interactions to enhance leukocyte activation.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD48. Following phosphorylation, it is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. Binding of SH2D1A/SAP to CD244 prevents its association with PTPN11/SHP-2.,tissue specificity:Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.,
Subcellular Locationplasma membrane,external side of plasma membrane,integral component of membrane,
ExpressionBlood,Lymphoid,Natural killer cell,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD244. AA range:101-150
Gene NameCD244
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
BackgroundCD244 molecule(CD244) Homo sapiens This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75615-Conjugate. Price: $485 / Size: 100μl.
E20-75615-FITC$485 / 100μlE20-75615-Biotin$485 / 100μlE20-75615-HRP$485 / 100μlE20-75615-AP$485 / 100μlE20-75615-AF350$485 / 100μlE20-75615-AF405M$485 / 100μlE20-75615-AF488$485 / 100μlE20-75615-AF514$485 / 100μlE20-75615-AF532$485 / 100μlE20-75615-AF555$485 / 100μlE20-75615-AF568$485 / 100μlE20-75615-AF405S$485 / 100μlE20-75615-AF405L$485 / 100μlE20-75615-AF546$485 / 100μlE20-75615-AF594$485 / 100μlE20-75615-AF610$485 / 100μlE20-75615-AF635$485 / 100μlE20-75615-AF647$485 / 100μlE20-75615-AF680$485 / 100μlE20-75615-AF700$485 / 100μlE20-75615-AF750$485 / 100μlE20-75615-AF790$485 / 100μlE20-75615-APC$485 / 100μlE20-75615-PE$485 / 100μlE20-75615-Cy3$485 / 100μlE20-75615-Cy5$485 / 100μlE20-75615-Cy5.5$485 / 100μlE20-75615-Cy7$485 / 100μlE20-75615-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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