Product Information
Molecular Weight41955Da
Protein NameC-X-C chemokine receptor type 5
Human Gene Id643
Human Swiss Prot NoP32302
Mouse Swiss Prot NoQ04683
SpecificityBlr1 Polyclonal Antibody detects endogenous levels of Blr1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCXCR5; BLR1; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; CD185
Observed Band(KD)42
Functionfunction:Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expression in mature B-cells and Burkitt lymphoma cells.,
Subcellular Locationplasma membrane,integral component of plasma membrane,external side of plasma membrane,integral component of membrane,
ExpressionBlood,Lymphocyte,
BackgroundC-X-C motif chemokine receptor 5(CXCR5) Homo sapiens This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],