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Cell Signal Transduction Research Antibodies
BST-2 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight19769Da
Protein NameBone marrow stromal antigen 2
Human Gene Id684
Human Swiss Prot NoQ10589
Mouse Swiss Prot NoQ8R2Q8
SpecificityBST-2 Polyclonal Antibody detects endogenous levels of BST-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBST2; Bone marrow stromal antigen 2; BST-2; HM1.24 antigen; Tetherin; CD317
Observed Band(KD)20
Functiondisease:May play a role in B-cell activation in rheumatoid arthritis (RA).,function:May be involved in the sorting of secreted proteins (By similarity). May be involved in pre-B-cell growth. Antiretroviral defense protein, that blocks release of retrovirus from the cell surface. Depleted unpon HIV-1 infection by viral VPU protein through 20S proteasome degradation.,induction:During B-cell activation (at protein level), or by interferon alpha as part of entiviral state cellular program.,subunit:Homodimer.,tissue specificity:Predominantly expressed in liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal muscle and brain. Overexpressed in multiple myeloma cells. Highly expressed during B-cell development, from pro-B precursors to plasma cells. Highy expressed on T-cells, monocytes, NK cells and dendritic cells (at protein level).,
Subcellular Locationcytoplasm,multivesicular body,Golgi apparatus,plasma membrane,integral component of plasma membrane,cell surface,membrane,integral component of membrane,apical plasma membrane,anchored component of membrane,membrane raft,GO
ExpressionBlood,Liver,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human BST2. AA range:101-150
Gene NameBST2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundbone marrow stromal cell antigen 2(BST2) Homo sapiens Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75612-Conjugate. Price: $485 / Size: 100μl.
E20-75612-FITC$485 / 100μlE20-75612-Biotin$485 / 100μlE20-75612-HRP$485 / 100μlE20-75612-AP$485 / 100μlE20-75612-AF350$485 / 100μlE20-75612-AF405M$485 / 100μlE20-75612-AF488$485 / 100μlE20-75612-AF514$485 / 100μlE20-75612-AF532$485 / 100μlE20-75612-AF555$485 / 100μlE20-75612-AF568$485 / 100μlE20-75612-AF405S$485 / 100μlE20-75612-AF405L$485 / 100μlE20-75612-AF546$485 / 100μlE20-75612-AF594$485 / 100μlE20-75612-AF610$485 / 100μlE20-75612-AF635$485 / 100μlE20-75612-AF647$485 / 100μlE20-75612-AF680$485 / 100μlE20-75612-AF700$485 / 100μlE20-75612-AF750$485 / 100μlE20-75612-AF790$485 / 100μlE20-75612-APC$485 / 100μlE20-75612-PE$485 / 100μlE20-75612-Cy3$485 / 100μlE20-75612-Cy5$485 / 100μlE20-75612-Cy5.5$485 / 100μlE20-75612-Cy7$485 / 100μlE20-75612-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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