World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
VE-Cadherin Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight87516Da
Protein NameCadherin-5
Human Gene Id1003
Human Swiss Prot NoP33151
Mouse Gene Id12562
Mouse Swiss Prot NoP55284
SpecificityVE-Cadherin Polyclonal Antibody detects endogenous levels of VE-Cadherin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144
Observed Band(KD)86
Functionfunction:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
Subcellular Locationplasma membrane,cell-cell junction,adherens junction,bicellular tight junction,external side of plasma membrane,cell surface,membrane,integral component of membrane,cell junction,
ExpressionAorta endothelial cell,Brain,Endothelial cell,PCR rescued clones,Placenta,Plasma,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CDH5. AA range:391-440
Gene NameCDH5
DilutionIF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Backgroundcadherin 5(CDH5) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015],
Conjugated Antibody
This product is also available conjugated. Format: E20-75611-Conjugate. Price: $485 / Size: 100μl.
E20-75611-FITC$485 / 100μlE20-75611-Biotin$485 / 100μlE20-75611-HRP$485 / 100μlE20-75611-AP$485 / 100μlE20-75611-AF350$485 / 100μlE20-75611-AF405M$485 / 100μlE20-75611-AF488$485 / 100μlE20-75611-AF514$485 / 100μlE20-75611-AF532$485 / 100μlE20-75611-AF555$485 / 100μlE20-75611-AF568$485 / 100μlE20-75611-AF405S$485 / 100μlE20-75611-AF405L$485 / 100μlE20-75611-AF546$485 / 100μlE20-75611-AF594$485 / 100μlE20-75611-AF610$485 / 100μlE20-75611-AF635$485 / 100μlE20-75611-AF647$485 / 100μlE20-75611-AF680$485 / 100μlE20-75611-AF700$485 / 100μlE20-75611-AF750$485 / 100μlE20-75611-AF790$485 / 100μlE20-75611-APC$485 / 100μlE20-75611-PE$485 / 100μlE20-75611-Cy3$485 / 100μlE20-75611-Cy5$485 / 100μlE20-75611-Cy5.5$485 / 100μlE20-75611-Cy7$485 / 100μlE20-75611-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits