Product Information
Molecular Weight32462Da
Protein NameSyndecan-1
Human Gene Id6382
Human Swiss Prot NoP18827
Mouse Swiss Prot NoP18828
SpecificityCD138 Polyclonal Antibody detects endogenous levels of CD138 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSDC1; SDC; Syndecan-1; SYND1; CD138
Observed Band(KD)34
Functionfunction:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Interacts with CDCP1.,
Subcellular Locationcytoplasm,Golgi lumen,plasma membrane,integral component of plasma membrane,focal adhesion,external side of plasma membrane,cell surface,membrane,lysosomal lumen,protein complex,extracellular exosome,
ExpressionDermoid cancer,Fibroblast,Kidney,Mammary gland,Placenta,
Backgroundsyndecan 1(SDC1) Homo sapiens The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008],