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Cell Signal Transduction Research Antibodies

Ron α Polyclonal Antibody

E20-75609Cite ID: EN0055742DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight152227Da
Protein NameMacrophage-stimulating protein receptor
Human Gene Id4486
Human Swiss Prot NoQ04912
Mouse Swiss Prot NoQ62190
SpecificityRon α Polyclonal Antibody detects endogenous levels of Ron α protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMST1R; PTK8; RON; Macrophage-stimulating protein receptor; MSP receptor; CDw136; Protein-tyrosine kinase 8; p185-Ron; CD136
Observed Band(KD)150
Functioncatalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.,PTM:Phosphorylated in response to ligand binding.,PTM:Proteolytic processing yields the two subunits.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Sema domain.,similarity:Contains 3 IPT/TIG domains.,subunit:Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2.,tissue specificity:Keratinocytes and lung.,
Subcellular Locationstress fiber,vacuole,plasma membrane,integral component of plasma membrane,cell surface,integral component of membrane,
ExpressionKeratinocyte,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human MST1R. AA range:31-80
Gene NameMST1R
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundmacrophage stimulating 1 receptor(MST1R) Homo sapiens This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],

Conjugated Antibody

This product is also available conjugated. Format: E20-75609-Conjugate. Price: $485 / Size: 100μl.

E20-75609-FITC$485 / 100μlE20-75609-Biotin$485 / 100μlE20-75609-HRP$485 / 100μlE20-75609-AP$485 / 100μlE20-75609-AF350$485 / 100μlE20-75609-AF405M$485 / 100μlE20-75609-AF488$485 / 100μlE20-75609-AF514$485 / 100μlE20-75609-AF532$485 / 100μlE20-75609-AF555$485 / 100μlE20-75609-AF568$485 / 100μlE20-75609-AF405S$485 / 100μlE20-75609-AF405L$485 / 100μlE20-75609-AF546$485 / 100μlE20-75609-AF594$485 / 100μlE20-75609-AF610$485 / 100μlE20-75609-AF635$485 / 100μlE20-75609-AF647$485 / 100μlE20-75609-AF680$485 / 100μlE20-75609-AF700$485 / 100μlE20-75609-AF750$485 / 100μlE20-75609-AF790$485 / 100μlE20-75609-APC$485 / 100μlE20-75609-PE$485 / 100μlE20-75609-Cy3$485 / 100μlE20-75609-Cy5$485 / 100μlE20-75609-Cy5.5$485 / 100μlE20-75609-Cy7$485 / 100μlE20-75609-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.