Flt3 Polyclonal Antibody

Name: Flt3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75608
Price: 225 USD
Availability: InStock

E20-75608Cite ID: EN0055741Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight112804Da

Protein NameReceptor-type tyrosine-protein kinase FLT3

Human Gene Id2322

Human Swiss Prot NoP36888

Mouse Gene Id14255

Mouse Swiss Prot NoQ00342

SpecificityFlt3 Polyclonal Antibody detects endogenous levels of Flt3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameFLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD135

Observed Band(KD)110

Functioncatalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for the FL cytokine. Has a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with FIZ1 following ligand activation.,tissue specificity:Bone marrow cells.,

Subcellular Locationnucleus,endoplasmic reticulum lumen,cytosol,plasma membrane,integral component of plasma membrane,integral component of membrane,protein complex,

ExpressionTestis,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FLT3. AA range:451-500

Gene NameFLT3

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundfms related tyrosine kinase 3(FLT3) Homo sapiens This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75608-Conjugate. Price: $485 / Size: 100μl.

E20-75608-FITC$485 / 100μlE20-75608-Biotin$485 / 100μlE20-75608-HRP$485 / 100μlE20-75608-AP$485 / 100μlE20-75608-AF350$485 / 100μlE20-75608-AF405M$485 / 100μlE20-75608-AF488$485 / 100μlE20-75608-AF514$485 / 100μlE20-75608-AF532$485 / 100μlE20-75608-AF555$485 / 100μlE20-75608-AF568$485 / 100μlE20-75608-AF405S$485 / 100μlE20-75608-AF405L$485 / 100μlE20-75608-AF546$485 / 100μlE20-75608-AF594$485 / 100μlE20-75608-AF610$485 / 100μlE20-75608-AF635$485 / 100μlE20-75608-AF647$485 / 100μlE20-75608-AF680$485 / 100μlE20-75608-AF700$485 / 100μlE20-75608-AF750$485 / 100μlE20-75608-AF790$485 / 100μlE20-75608-APC$485 / 100μlE20-75608-PE$485 / 100μlE20-75608-Cy3$485 / 100μlE20-75608-Cy5$485 / 100μlE20-75608-Cy5.5$485 / 100μlE20-75608-Cy7$485 / 100μlE20-75608-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.