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Cell Signal Transduction Research Antibodies

Nectin 2 Polyclonal Antibody

E20-75603Cite ID: EN0055736DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight57742Da
Protein NamePoliovirus receptor-related protein 2
Human Gene Id5819
Human Swiss Prot NoQ92692
Mouse Swiss Prot NoP32507
SpecificityNectin 2 Polyclonal Antibody detects endogenous levels of Nectin 2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePVRL2; HVEB; PRR2; Poliovirus receptor-related protein 2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin-2; CD112
Observed Band(KD)65
Functionfunction:Probable cell adhesion protein.,similarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Can form trans-heterodimers with PVRL3/nectin-3 (By similarity). Interacts with CD226. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells. Binds with low affinity to TIGIT.,tissue specificity:Ubiquitous.,
Subcellular Locationplasma membrane,integral component of plasma membrane,cell-cell junction,cell-cell adherens junction,zonula adherens,focal adhesion,cell surface,integral component of membrane,cell-cell contact zone,extracellular exosome,
ExpressionBrain,Epithelium,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from Poliovirus receptor-related protein 2 at AA range: 151-200
Gene NamePVRL2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundnectin cell adhesion molecule 2(NECTIN2) Homo sapiens This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75603-Conjugate. Price: $485 / Size: 100μl.

E20-75603-FITC$485 / 100μlE20-75603-Biotin$485 / 100μlE20-75603-HRP$485 / 100μlE20-75603-AP$485 / 100μlE20-75603-AF350$485 / 100μlE20-75603-AF405M$485 / 100μlE20-75603-AF488$485 / 100μlE20-75603-AF514$485 / 100μlE20-75603-AF532$485 / 100μlE20-75603-AF555$485 / 100μlE20-75603-AF568$485 / 100μlE20-75603-AF405S$485 / 100μlE20-75603-AF405L$485 / 100μlE20-75603-AF546$485 / 100μlE20-75603-AF594$485 / 100μlE20-75603-AF610$485 / 100μlE20-75603-AF635$485 / 100μlE20-75603-AF647$485 / 100μlE20-75603-AF680$485 / 100μlE20-75603-AF700$485 / 100μlE20-75603-AF750$485 / 100μlE20-75603-AF790$485 / 100μlE20-75603-APC$485 / 100μlE20-75603-PE$485 / 100μlE20-75603-Cy3$485 / 100μlE20-75603-Cy5$485 / 100μlE20-75603-Cy5.5$485 / 100μlE20-75603-Cy7$485 / 100μlE20-75603-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.