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Cell Signal Transduction Research Antibodies

ICAM-2 Polyclonal Antibody

E20-75601Cite ID: EN0055734DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight30654Da
Protein NameIntercellular adhesion molecule 2
Human Gene Id3384
Human Swiss Prot NoP13598
Mouse Swiss Prot NoP35330
SpecificityICAM-2 Polyclonal Antibody detects endogenous levels of ICAM-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameICAM2; Intercellular adhesion molecule 2; ICAM-2; CD102
Observed Band(KD)30
Functionfunction:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.,online information:ICAM-2,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
Subcellular Locationuropod,plasma membrane,integral component of plasma membrane,membrane,integral component of membrane,extracellular exosome,
ExpressionAorta endothelial cell,Blood,Brain,Endothelial cell,Plasma,Spleen,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ICAM2. AA range:141-190
Gene NameICAM2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundintercellular adhesion molecule 2(ICAM2) Homo sapiens The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75601-Conjugate. Price: $485 / Size: 100μl.

E20-75601-FITC$485 / 100μlE20-75601-Biotin$485 / 100μlE20-75601-HRP$485 / 100μlE20-75601-AP$485 / 100μlE20-75601-AF350$485 / 100μlE20-75601-AF405M$485 / 100μlE20-75601-AF488$485 / 100μlE20-75601-AF514$485 / 100μlE20-75601-AF532$485 / 100μlE20-75601-AF555$485 / 100μlE20-75601-AF568$485 / 100μlE20-75601-AF405S$485 / 100μlE20-75601-AF405L$485 / 100μlE20-75601-AF546$485 / 100μlE20-75601-AF594$485 / 100μlE20-75601-AF610$485 / 100μlE20-75601-AF635$485 / 100μlE20-75601-AF647$485 / 100μlE20-75601-AF680$485 / 100μlE20-75601-AF700$485 / 100μlE20-75601-AF750$485 / 100μlE20-75601-AF790$485 / 100μlE20-75601-APC$485 / 100μlE20-75601-PE$485 / 100μlE20-75601-Cy3$485 / 100μlE20-75601-Cy5$485 / 100μlE20-75601-Cy5.5$485 / 100μlE20-75601-Cy7$485 / 100μlE20-75601-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.