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Cell Signal Transduction Research Antibodies
CD101 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight115073Da
Protein NameImmunoglobulin superfamily member 2
Human Gene Id9398
Human Swiss Prot NoQ93033
Mouse Swiss Prot NoA8E0Y8
SpecificityCD101 Polyclonal Antibody detects endogenous levels of CD101 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD101; EWI101; IGSF2; V7; Immunoglobulin superfamily member 2; IgSF2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101
Observed Band(KD)130
Functionfunction:Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.,PTM:N-glycosylated.,similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphol
Subcellular Locationplasma membrane,integral component of membrane,extracellular exosome,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD101. AA range:731-780
Gene NameCD101
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundfunction:Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.,PTM:N-glycosylated.,similarity:Contains 7 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.,
Conjugated Antibody
This product is also available conjugated. Format: E20-75600-Conjugate. Price: $485 / Size: 100μl.
E20-75600-FITC$485 / 100μlE20-75600-Biotin$485 / 100μlE20-75600-HRP$485 / 100μlE20-75600-AP$485 / 100μlE20-75600-AF350$485 / 100μlE20-75600-AF405M$485 / 100μlE20-75600-AF488$485 / 100μlE20-75600-AF514$485 / 100μlE20-75600-AF532$485 / 100μlE20-75600-AF555$485 / 100μlE20-75600-AF568$485 / 100μlE20-75600-AF405S$485 / 100μlE20-75600-AF405L$485 / 100μlE20-75600-AF546$485 / 100μlE20-75600-AF594$485 / 100μlE20-75600-AF610$485 / 100μlE20-75600-AF635$485 / 100μlE20-75600-AF647$485 / 100μlE20-75600-AF680$485 / 100μlE20-75600-AF700$485 / 100μlE20-75600-AF750$485 / 100μlE20-75600-AF790$485 / 100μlE20-75600-APC$485 / 100μlE20-75600-PE$485 / 100μlE20-75600-Cy3$485 / 100μlE20-75600-Cy5$485 / 100μlE20-75600-Cy5.5$485 / 100μlE20-75600-Cy7$485 / 100μlE20-75600-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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