CD66c/d Polyclonal Antibody

Name: CD66c/d Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75594
Price: 225 USD
Availability: InStock

E20-75594Cite ID: EN0055727Datasheet COA MSDS

Source：Polyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight：27720Da

Protein Name：Carcinoembryonic antigen-related cell adhesion molecule 3/Carcinoembryonic antigen-related cell adhesion molecule 6

Human Gene Id：1084/4680

Human Swiss Prot No：P40198/P40199

Specificity：CD66c/d Polyclonal Antibody detects endogenous levels of CD66c/d protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration：1 mg/ml

Storage Stability：-20°C/1 year

Other Name：CEACAM3; CD66D; CGM1; Carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen CGM1; CD66d; CEACAM6; NCA; Carcinoembryonic antigen-related cell adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD66c

Observed Band(KD)：30

Function：caution:This is not the ortholog of rat CEACAM3.,domain:The cytosolic domain is involved in S100A9 interaction.,function:Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.,PTM:Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with S100A9/calprotectin. This interaction is calcium-dependent, but independent of CEACAM3 phosphorylation.,tissue specificity:CGM1a, the pred

Subcellular Location：integral component of membrane,

Expression：Leukocyte,Liver,

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6. AA range:31-80

Gene Name：CEACAM3/CEACAM6

Dilution：Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background：carcinoembryonic antigen related cell adhesion molecule 3(CEACAM3) Homo sapiens This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75594-Conjugate. Price: $485 / Size: 100μl.

E20-75594-FITC$485 / 100μlE20-75594-Biotin$485 / 100μlE20-75594-HRP$485 / 100μlE20-75594-AP$485 / 100μlE20-75594-AF350$485 / 100μlE20-75594-AF405M$485 / 100μlE20-75594-AF488$485 / 100μlE20-75594-AF514$485 / 100μlE20-75594-AF532$485 / 100μlE20-75594-AF555$485 / 100μlE20-75594-AF568$485 / 100μlE20-75594-AF405S$485 / 100μlE20-75594-AF405L$485 / 100μlE20-75594-AF546$485 / 100μlE20-75594-AF594$485 / 100μlE20-75594-AF610$485 / 100μlE20-75594-AF635$485 / 100μlE20-75594-AF647$485 / 100μlE20-75594-AF680$485 / 100μlE20-75594-AF700$485 / 100μlE20-75594-AF750$485 / 100μlE20-75594-AF790$485 / 100μlE20-75594-APC$485 / 100μlE20-75594-PE$485 / 100μlE20-75594-Cy3$485 / 100μlE20-75594-Cy5$485 / 100μlE20-75594-Cy5.5$485 / 100μlE20-75594-Cy7$485 / 100μlE20-75594-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.