World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CD53 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight24341Da
Protein NameLeukocyte surface antigen CD53
Human Gene Id963
Human Swiss Prot NoP19397
Mouse Gene Id12508
Mouse Swiss Prot NoQ61451
Rat Gene Id24251
Rat Swiss Prot NoP24485
SpecificityCD53 Polyclonal Antibody detects endogenous levels of CD53 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD53
Observed Band(KD)24
Functionfunction:May be involved in growth regulation in hematopoietic cells.,similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.,
Subcellular Locationimmunological synapse,plasma membrane,integral component of plasma membrane,cell-cell junction,cell surface,integral component of membrane,extracellular exosome,
ExpressionLymph,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140
Gene NameCD53
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundCD53 molecule(CD53) Homo sapiens The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Conjugated Antibody
This product is also available conjugated. Format: E20-75591-Conjugate. Price: $485 / Size: 100μl.
E20-75591-FITC$485 / 100μlE20-75591-Biotin$485 / 100μlE20-75591-HRP$485 / 100μlE20-75591-AP$485 / 100μlE20-75591-AF350$485 / 100μlE20-75591-AF405M$485 / 100μlE20-75591-AF488$485 / 100μlE20-75591-AF514$485 / 100μlE20-75591-AF532$485 / 100μlE20-75591-AF555$485 / 100μlE20-75591-AF568$485 / 100μlE20-75591-AF405S$485 / 100μlE20-75591-AF405L$485 / 100μlE20-75591-AF546$485 / 100μlE20-75591-AF594$485 / 100μlE20-75591-AF610$485 / 100μlE20-75591-AF635$485 / 100μlE20-75591-AF647$485 / 100μlE20-75591-AF680$485 / 100μlE20-75591-AF700$485 / 100μlE20-75591-AF750$485 / 100μlE20-75591-AF790$485 / 100μlE20-75591-APC$485 / 100μlE20-75591-PE$485 / 100μlE20-75591-Cy3$485 / 100μlE20-75591-Cy5$485 / 100μlE20-75591-Cy5.5$485 / 100μlE20-75591-Cy7$485 / 100μlE20-75591-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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