World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CD42d Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight61600Da
Protein NamePlatelet glycoprotein V
Human Gene Id2814
Human Swiss Prot NoP40197
Mouse Swiss Prot NoO08742
Rat Gene Id25259
Rat Swiss Prot NoO08770
SpecificityCD42d Polyclonal Antibody detects endogenous levels of CD42d protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameGP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d
Observed Band(KD)62
Functionfunction:The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.,PTM:The N-terminus is blocked.,similarity:Contains 14 LRR (leucine-rich) repeats.,tissue specificity:Platelets and megakaryocytes.,
Subcellular Locationplasma membrane,integral component of plasma membrane,extracellular exosome,
ExpressionLung,Platelet,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human GP5. AA range:331-380
Gene NameGP5
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundglycoprotein V platelet(GP5) Homo sapiens Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-75587-Conjugate. Price: $485 / Size: 100μl.
E20-75587-FITC$485 / 100μlE20-75587-Biotin$485 / 100μlE20-75587-HRP$485 / 100μlE20-75587-AP$485 / 100μlE20-75587-AF350$485 / 100μlE20-75587-AF405M$485 / 100μlE20-75587-AF488$485 / 100μlE20-75587-AF514$485 / 100μlE20-75587-AF532$485 / 100μlE20-75587-AF555$485 / 100μlE20-75587-AF568$485 / 100μlE20-75587-AF405S$485 / 100μlE20-75587-AF405L$485 / 100μlE20-75587-AF546$485 / 100μlE20-75587-AF594$485 / 100μlE20-75587-AF610$485 / 100μlE20-75587-AF635$485 / 100μlE20-75587-AF647$485 / 100μlE20-75587-AF680$485 / 100μlE20-75587-AF700$485 / 100μlE20-75587-AF750$485 / 100μlE20-75587-AF790$485 / 100μlE20-75587-APC$485 / 100μlE20-75587-PE$485 / 100μlE20-75587-Cy3$485 / 100μlE20-75587-Cy5$485 / 100μlE20-75587-Cy5.5$485 / 100μlE20-75587-Cy7$485 / 100μlE20-75587-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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