Product Information
Molecular Weight57965Da
Protein NameEctonucleoside triphosphate diphosphohydrolase 1
Human Gene Id953
Human Swiss Prot NoP49961
Mouse Gene Id12495
Mouse Swiss Prot NoP55772
Rat Gene Id64519
Rat Swiss Prot NoP97687
SpecificityCD39 Polyclonal Antibody detects endogenous levels of CD39 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameENTPD1; CD39; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39
Observed Band(KD)56
Functioncatalytic activity:ATP + 2 H(2)O = AMP + 2 phosphate.,cofactor:Calcium.,cofactor:Magnesium.,function:In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.,PTM:Palmitoylated in the N-terminal part.,PTM:The N-terminus is blocked.,similarity:Belongs to the GDA1/CD39 NTPase family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.,
Subcellular Locationplasma membrane,integral component of plasma membrane,membrane,integral component of membrane,extracellular exosome,
ExpressionBrain,Liver,Lung,Placenta,Synovial membrane tissue,
Backgroundectonucleoside triphosphate diphosphohydrolase 1(ENTPD1) Homo sapiens The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015],