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Cell Signal Transduction Research Antibodies

CD36 Polyclonal Antibody

E20-75585Cite ID: EN0055718DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight53053Da
Protein NamePlatelet glycoprotein 4
Human Gene Id948
Human Swiss Prot NoP16671
Mouse Gene Id12491
Mouse Swiss Prot NoQ08857
Rat Swiss Prot NoQ07969
SpecificityCD36 Polyclonal Antibody detects endogenous levels of CD36 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36
Observed Band(KD)90
Functiondisease:Defects in CD36 are the cause of platelet glycoprotein IV deficiency [MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal.,disease:Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].,function:Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a
Subcellular Locationcollagen trimer,extracellular space,Golgi apparatus,plasma membrane,integral component of plasma membrane,external side of plasma membrane,cell surface,membrane,integral component of membrane,apical plasma membrane,endocytic vesicle membrane,
ExpressionAdipocyte,Liver,Mammary gland,Milk,Placenta,Platelet,Skeletal muscle,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD36. AA range:331-380
Gene NameCD36
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
BackgroundCD36 molecule(CD36) Homo sapiens The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014],

Conjugated Antibody

This product is also available conjugated. Format: E20-75585-Conjugate. Price: $485 / Size: 100μl.

E20-75585-FITC$485 / 100μlE20-75585-Biotin$485 / 100μlE20-75585-HRP$485 / 100μlE20-75585-AP$485 / 100μlE20-75585-AF350$485 / 100μlE20-75585-AF405M$485 / 100μlE20-75585-AF488$485 / 100μlE20-75585-AF514$485 / 100μlE20-75585-AF532$485 / 100μlE20-75585-AF555$485 / 100μlE20-75585-AF568$485 / 100μlE20-75585-AF405S$485 / 100μlE20-75585-AF405L$485 / 100μlE20-75585-AF546$485 / 100μlE20-75585-AF594$485 / 100μlE20-75585-AF610$485 / 100μlE20-75585-AF635$485 / 100μlE20-75585-AF647$485 / 100μlE20-75585-AF680$485 / 100μlE20-75585-AF700$485 / 100μlE20-75585-AF750$485 / 100μlE20-75585-AF790$485 / 100μlE20-75585-APC$485 / 100μlE20-75585-PE$485 / 100μlE20-75585-Cy3$485 / 100μlE20-75585-Cy5$485 / 100μlE20-75585-Cy5.5$485 / 100μlE20-75585-Cy7$485 / 100μlE20-75585-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.