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Cell Signal Transduction Research Antibodies
CD21 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight112916Da
Protein NameComplement receptor type 2
Human Gene Id1380
Human Swiss Prot NoP20023
Mouse Swiss Prot NoP19070
SpecificityCD21 Polyclonal Antibody detects endogenous levels of CD21 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCR2; C3DR; Complement receptor type 2; Cr2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptor; CD21
Observed Band(KD)115
Functiondisease:Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.,function:Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.,similarity:Belongs to the receptors of complement activation (RCA) family.,similarity:Contains 15 Sushi (CCP/SCR) domains.,tissue specificity:Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells
Subcellular Locationplasma membrane,integral component of membrane,receptor complex,extracellular exosome,
ExpressionB-cell,Lymph,Pooled,Spleen,Synovial membrane tissue,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CR2. AA range:381-430
Gene NameCR2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundcomplement C3d receptor 2(CR2) Homo sapiens This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-75582-Conjugate. Price: $485 / Size: 100μl.
E20-75582-FITC$485 / 100μlE20-75582-Biotin$485 / 100μlE20-75582-HRP$485 / 100μlE20-75582-AP$485 / 100μlE20-75582-AF350$485 / 100μlE20-75582-AF405M$485 / 100μlE20-75582-AF488$485 / 100μlE20-75582-AF514$485 / 100μlE20-75582-AF532$485 / 100μlE20-75582-AF555$485 / 100μlE20-75582-AF568$485 / 100μlE20-75582-AF405S$485 / 100μlE20-75582-AF405L$485 / 100μlE20-75582-AF546$485 / 100μlE20-75582-AF594$485 / 100μlE20-75582-AF610$485 / 100μlE20-75582-AF635$485 / 100μlE20-75582-AF647$485 / 100μlE20-75582-AF680$485 / 100μlE20-75582-AF700$485 / 100μlE20-75582-AF750$485 / 100μlE20-75582-AF790$485 / 100μlE20-75582-APC$485 / 100μlE20-75582-PE$485 / 100μlE20-75582-Cy3$485 / 100μlE20-75582-Cy5$485 / 100μlE20-75582-Cy5.5$485 / 100μlE20-75582-Cy7$485 / 100μlE20-75582-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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