CD20 Polyclonal Antibody

Name: CD20 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75581
Price: 225 USD
Availability: InStock

E20-75581Cite ID: EN0055714Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight33077Da

Protein NameB-lymphocyte antigen CD20

Human Gene Id931

Human Swiss Prot NoP11836

Mouse Swiss Prot NoP19437

SpecificityCD20 Polyclonal Antibody detects endogenous levels of CD20 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameMS4A1; CD20; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD20

Observed Band(KD)28

Functioncaution:Epitope 1, mapped in PubMed:16785532, is predicted to be buried in the membrane. Its accessibility to the extracellular space, and thus to antibody recognition, is not explained.,function:This protein may be involved in the regulation of B-cell activation and proliferation.,online information:CD20 entry,pharmaceutical:Monoclonal antibodies(mAb) against CD20 are used to treat B-cell non-Hodgkin's lymphoma (NHL). These antibodies include Rituximab (Mabthera), Britumomab (Zevalin) and Tositumomab (Bexxar). CD20 engaged by mAb can generate transmembrane signals capable of directly controlling cell growth and triggering cell death in certain tumors. Alternatively, mAb can mediate complement-dependent cytotoxicity.,PTM:Phosphorylated. Might be functionally regulated by protein kinase(s).,similarity:Belongs to the MS4A family.,tissue specificity:Expressed on B-cells.,

Subcellular Locationextracellular space,integral component of plasma membrane,external side of plasma membrane,extracellular exosome,

ExpressionLymph,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MS4A1. AA range:201-250

Gene NameMS4A1

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundmembrane spanning 4-domains A1(MS4A1) Homo sapiens This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75581-Conjugate. Price: $485 / Size: 100μl.

E20-75581-FITC$485 / 100μlE20-75581-Biotin$485 / 100μlE20-75581-HRP$485 / 100μlE20-75581-AP$485 / 100μlE20-75581-AF350$485 / 100μlE20-75581-AF405M$485 / 100μlE20-75581-AF488$485 / 100μlE20-75581-AF514$485 / 100μlE20-75581-AF532$485 / 100μlE20-75581-AF555$485 / 100μlE20-75581-AF568$485 / 100μlE20-75581-AF405S$485 / 100μlE20-75581-AF405L$485 / 100μlE20-75581-AF546$485 / 100μlE20-75581-AF594$485 / 100μlE20-75581-AF610$485 / 100μlE20-75581-AF635$485 / 100μlE20-75581-AF647$485 / 100μlE20-75581-AF680$485 / 100μlE20-75581-AF700$485 / 100μlE20-75581-AF750$485 / 100μlE20-75581-AF790$485 / 100μlE20-75581-APC$485 / 100μlE20-75581-PE$485 / 100μlE20-75581-Cy3$485 / 100μlE20-75581-Cy5$485 / 100μlE20-75581-Cy5.5$485 / 100μlE20-75581-Cy7$485 / 100μlE20-75581-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.