Integrin αL Polyclonal Antibody

Name: Integrin αL Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75578
Price: 225 USD
Availability: InStock

E20-75578Cite ID: EN0055711Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight128770Da

Protein NameIntegrin alpha-L

Human Gene Id3683

Human Swiss Prot NoP20701

Mouse Swiss Prot NoP24063

SpecificityIntegrin αL Polyclonal Antibody detects endogenous levels of Integrin αL protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameITGAL; CD11A; Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD11a

Observed Band(KD)130

Functiondomain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2.,tissue specificity:Leukocytes.,

Subcellular Locationplasma membrane,integrin complex,cell surface,membrane,integral component of membrane,integrin alphaL-beta2 complex,extracellular exosome,

ExpressionLymph,Trachea,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human ITGAL. AA range:171-220

Gene NameITGAL

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundintegrin subunit alpha L(ITGAL) Homo sapiens ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75578-Conjugate. Price: $485 / Size: 100μl.

E20-75578-FITC$485 / 100μlE20-75578-Biotin$485 / 100μlE20-75578-HRP$485 / 100μlE20-75578-AP$485 / 100μlE20-75578-AF350$485 / 100μlE20-75578-AF405M$485 / 100μlE20-75578-AF488$485 / 100μlE20-75578-AF514$485 / 100μlE20-75578-AF532$485 / 100μlE20-75578-AF555$485 / 100μlE20-75578-AF568$485 / 100μlE20-75578-AF405S$485 / 100μlE20-75578-AF405L$485 / 100μlE20-75578-AF546$485 / 100μlE20-75578-AF594$485 / 100μlE20-75578-AF610$485 / 100μlE20-75578-AF635$485 / 100μlE20-75578-AF647$485 / 100μlE20-75578-AF680$485 / 100μlE20-75578-AF700$485 / 100μlE20-75578-AF750$485 / 100μlE20-75578-AF790$485 / 100μlE20-75578-APC$485 / 100μlE20-75578-PE$485 / 100μlE20-75578-Cy3$485 / 100μlE20-75578-Cy5$485 / 100μlE20-75578-Cy5.5$485 / 100μlE20-75578-Cy7$485 / 100μlE20-75578-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.