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Cell Signal Transduction Research Antibodies
CD6 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight71829Da
Protein NameT-cell differentiation antigen CD6
Human Gene Id923
Human Swiss Prot NoP30203
Mouse Swiss Prot NoQ61003
SpecificityCD6 Polyclonal Antibody detects endogenous levels of CD6 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCD6; T-cell differentiation antigen CD6; T12; TP120; CD6
Observed Band(KD)73
Functionfunction:Involved in cell adhesion. Binds to CD166.,PTM:After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.,PTM:Contains intrachain disulfide bond(s).,similarity:Contains 3 SRCR domains.,tissue specificity:Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.,
Subcellular Locationimmunological synapse,extracellular region,integral component of plasma membrane,membrane,integral component of membrane,intrinsic component of plasma membrane,T cell receptor complex,
ExpressionBlood,Placenta,Spleen,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD6. AA range:361-410
Gene NameCD6
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
BackgroundCD6 molecule(CD6) Homo sapiens This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-75577-Conjugate. Price: $485 / Size: 100μl.
E20-75577-FITC$485 / 100μlE20-75577-Biotin$485 / 100μlE20-75577-HRP$485 / 100μlE20-75577-AP$485 / 100μlE20-75577-AF350$485 / 100μlE20-75577-AF405M$485 / 100μlE20-75577-AF488$485 / 100μlE20-75577-AF514$485 / 100μlE20-75577-AF532$485 / 100μlE20-75577-AF555$485 / 100μlE20-75577-AF568$485 / 100μlE20-75577-AF405S$485 / 100μlE20-75577-AF405L$485 / 100μlE20-75577-AF546$485 / 100μlE20-75577-AF594$485 / 100μlE20-75577-AF610$485 / 100μlE20-75577-AF635$485 / 100μlE20-75577-AF647$485 / 100μlE20-75577-AF680$485 / 100μlE20-75577-AF700$485 / 100μlE20-75577-AF750$485 / 100μlE20-75577-AF790$485 / 100μlE20-75577-APC$485 / 100μlE20-75577-PE$485 / 100μlE20-75577-Cy3$485 / 100μlE20-75577-Cy5$485 / 100μlE20-75577-Cy5.5$485 / 100μlE20-75577-Cy7$485 / 100μlE20-75577-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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