IL-3Rα Polyclonal Antibody

Name: IL-3Rα Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75570
Price: 225 USD
Availability: InStock

E20-75570Cite ID: EN0055703Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight41580Da

Protein NameInterleukin-3 receptor subunit alpha

Human Gene Id3563

Human Swiss Prot NoP26951

Mouse Swiss Prot NoP26952

SpecificityIL-3Rα Polyclonal Antibody detects endogenous levels of IL-3Rα protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameIL3RA; IL3R; Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123

Observed Band(KD)42

Functiondomain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:This is a receptor for interleukin-3.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,

Subcellular Locationintracellular,plasma membrane,membrane,integral component of membrane,

ExpressionBrain,Lung,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human IL3RA. AA range:241-290

Gene NameIL3RA

DilutionIHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundinterleukin 3 receptor subunit alpha(IL3RA) Homo sapiens The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75570-Conjugate. Price: $485 / Size: 100μl.

E20-75570-FITC$485 / 100μlE20-75570-Biotin$485 / 100μlE20-75570-HRP$485 / 100μlE20-75570-AP$485 / 100μlE20-75570-AF350$485 / 100μlE20-75570-AF405M$485 / 100μlE20-75570-AF488$485 / 100μlE20-75570-AF514$485 / 100μlE20-75570-AF532$485 / 100μlE20-75570-AF555$485 / 100μlE20-75570-AF568$485 / 100μlE20-75570-AF405S$485 / 100μlE20-75570-AF405L$485 / 100μlE20-75570-AF546$485 / 100μlE20-75570-AF594$485 / 100μlE20-75570-AF610$485 / 100μlE20-75570-AF635$485 / 100μlE20-75570-AF647$485 / 100μlE20-75570-AF680$485 / 100μlE20-75570-AF700$485 / 100μlE20-75570-AF750$485 / 100μlE20-75570-AF790$485 / 100μlE20-75570-APC$485 / 100μlE20-75570-PE$485 / 100μlE20-75570-Cy3$485 / 100μlE20-75570-Cy5$485 / 100μlE20-75570-Cy5.5$485 / 100μlE20-75570-Cy7$485 / 100μlE20-75570-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.