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Cell Signal Transduction Research Antibodies
CD89 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight32265Da
Protein NameImmunoglobulin alpha Fc receptor
Human Gene Id2204
Human Swiss Prot NoP24071
SpecificityCD89 Polyclonal Antibody detects endogenous levels of CD89 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89
Observed Band(KD)32
Functionalternative products:Additional isoforms seem to exist,function:Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.,tissue specificity:Differentially expressed between blood and mucosal myeloid cells. Monocytes express isoform A.1, isoform A.2 and isoform A.3 while alveolar macrophages express isoform A.1 and isoform A.2; however they express only one isoform at their surfaces.,
Subcellular Locationextracellular region,plasma membrane,integral component of plasma membrane,integral component of membrane,
ExpressionAlveolar macrophage,Blood,Bone marrow,Monocyte,Pituitary,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FCAR. AA range:31-80
Gene NameFCAR
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
BackgroundFc fragment of IgA receptor(FCAR) Homo sapiens This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Western Blot analysis of NIH-3T3 cells using CD89 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000.
Conjugated Antibody
This product is also available conjugated. Format: E20-75568-Conjugate. Price: $485 / Size: 100μl.
E20-75568-FITC$485 / 100μlE20-75568-Biotin$485 / 100μlE20-75568-HRP$485 / 100μlE20-75568-AP$485 / 100μlE20-75568-AF350$485 / 100μlE20-75568-AF405M$485 / 100μlE20-75568-AF488$485 / 100μlE20-75568-AF514$485 / 100μlE20-75568-AF532$485 / 100μlE20-75568-AF555$485 / 100μlE20-75568-AF568$485 / 100μlE20-75568-AF405S$485 / 100μlE20-75568-AF405L$485 / 100μlE20-75568-AF546$485 / 100μlE20-75568-AF594$485 / 100μlE20-75568-AF610$485 / 100μlE20-75568-AF635$485 / 100μlE20-75568-AF647$485 / 100μlE20-75568-AF680$485 / 100μlE20-75568-AF700$485 / 100μlE20-75568-AF750$485 / 100μlE20-75568-AF790$485 / 100μlE20-75568-APC$485 / 100μlE20-75568-PE$485 / 100μlE20-75568-Cy3$485 / 100μlE20-75568-Cy5$485 / 100μlE20-75568-Cy5.5$485 / 100μlE20-75568-Cy7$485 / 100μlE20-75568-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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