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Cell Signal Transduction Research Antibodies
NGF Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight26959Da
Protein NameBeta-nerve growth factor
Human Gene Id4803
Human Swiss Prot NoP01138
Mouse Swiss Prot NoP01139
SpecificityNGF Polyclonal Antibody detects endogenous levels of NGF protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNGF; NGFB; Beta-nerve growth factor; Beta-NGF
Observed Band(KD)27
Functiondisease:Defects in NGF are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable.,function:Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.,online information:Nerve growth factor entry,similarity:Belongs to the NGF-beta family.,subunit:Homodimer.,
Subcellular Locationextracellular region,endosome,Golgi lumen,cytoplasmic, membrane-bounded vesicle,
ExpressionBrain,Epithelium,Eye,Leukocyte,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human NGF. AA range:141-190
Gene NameNGF
DilutionWB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Backgroundnerve growth factor(NGF) Homo sapiens This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75565-Conjugate. Price: $485 / Size: 100μl.
E20-75565-FITC$485 / 100μlE20-75565-Biotin$485 / 100μlE20-75565-HRP$485 / 100μlE20-75565-AP$485 / 100μlE20-75565-AF350$485 / 100μlE20-75565-AF405M$485 / 100μlE20-75565-AF488$485 / 100μlE20-75565-AF514$485 / 100μlE20-75565-AF532$485 / 100μlE20-75565-AF555$485 / 100μlE20-75565-AF568$485 / 100μlE20-75565-AF405S$485 / 100μlE20-75565-AF405L$485 / 100μlE20-75565-AF546$485 / 100μlE20-75565-AF594$485 / 100μlE20-75565-AF610$485 / 100μlE20-75565-AF635$485 / 100μlE20-75565-AF647$485 / 100μlE20-75565-AF680$485 / 100μlE20-75565-AF700$485 / 100μlE20-75565-AF750$485 / 100μlE20-75565-AF790$485 / 100μlE20-75565-APC$485 / 100μlE20-75565-PE$485 / 100μlE20-75565-Cy3$485 / 100μlE20-75565-Cy5$485 / 100μlE20-75565-Cy5.5$485 / 100μlE20-75565-Cy7$485 / 100μlE20-75565-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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