Product Information
Molecular Weight28672Da
Protein NameDickkopf-related protein 1
Human Gene Id22943
Human Swiss Prot NoO94907
Mouse Gene Id13380
Mouse Swiss Prot NoO54908
SpecificityDkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK
Observed Band(KD)29
Functionfunction:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta.,
Subcellular Locationextracellular region,extracellular space,plasma membrane,early endosome membrane,
ExpressionBrain,Fetal kidney,Leiomyosarcoma,
Backgrounddickkopf WNT signaling pathway inhibitor 1(DKK1) Homo sapiens This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],