RGS1 Polyclonal Antibody

Name: RGS1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75559
Price: 225 USD
Availability: InStock

E20-75559Cite ID: EN0055692Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight22475Da

Protein NameRegulator of G-protein signaling 1

Human Gene Id5996

Human Swiss Prot NoQ08116

Mouse Gene Id50778

Mouse Swiss Prot NoQ9JL25

Rat Gene Id54289

Rat Swiss Prot NoP97844

SpecificityRGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameRGS1; 1R20; BL34; IER1; Regulator of G-protein signaling 1; RGS1; B-cell activation protein BL34; Early response protein 1R20

Observed Band(KD)23

Functionfunction:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.,induction:In response to several B-cell activation signals.,PTM:Could be phosphorylated. Might be functionally regulated by protein kinase(s).,similarity:Contains 1 RGS domain.,tissue specificity:B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin's lymphoma and hairy cell leukemia, expression is constitutively high.,

Subcellular Locationcytosol,plasma membrane,extrinsic component of cytoplasmic side of plasma membrane,

ExpressionB-cell,Skeletal muscle,Skin,Thymus,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human RGS1. AA range:160-209

Gene NameRGS1

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Backgroundregulator of G-protein signaling 1(RGS1) Homo sapiens This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75559-Conjugate. Price: $485 / Size: 100μl.

E20-75559-FITC$485 / 100μlE20-75559-Biotin$485 / 100μlE20-75559-HRP$485 / 100μlE20-75559-AP$485 / 100μlE20-75559-AF350$485 / 100μlE20-75559-AF405M$485 / 100μlE20-75559-AF488$485 / 100μlE20-75559-AF514$485 / 100μlE20-75559-AF532$485 / 100μlE20-75559-AF555$485 / 100μlE20-75559-AF568$485 / 100μlE20-75559-AF405S$485 / 100μlE20-75559-AF405L$485 / 100μlE20-75559-AF546$485 / 100μlE20-75559-AF594$485 / 100μlE20-75559-AF610$485 / 100μlE20-75559-AF635$485 / 100μlE20-75559-AF647$485 / 100μlE20-75559-AF680$485 / 100μlE20-75559-AF700$485 / 100μlE20-75559-AF750$485 / 100μlE20-75559-AF790$485 / 100μlE20-75559-APC$485 / 100μlE20-75559-PE$485 / 100μlE20-75559-Cy3$485 / 100μlE20-75559-Cy5$485 / 100μlE20-75559-Cy5.5$485 / 100μlE20-75559-Cy7$485 / 100μlE20-75559-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.