Product Information
Molecular Weight36908Da
Protein NameStimulated by retinoic acid gene 8 protein homolog
Human Gene Id346673
Human Swiss Prot NoQ7Z7C7
Mouse Swiss Prot NoP70278
SpecificityStra8 Polyclonal Antibody detects endogenous levels of Stra8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSTRA8; Stimulated by retinoic acid gene 8 protein homolog
Observed Band(KD)66
Functionfunction:Required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.,PTM:Phosphorylated.,tissue specificity:Expressed specifically in testis.,
Subcellular Locationnucleus,cytoplasm,
Backgroundstimulated by retinoic acid 8(STRA8) Homo sapiens This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010],