Product Information
Molecular Weight24891Da
Protein NameFibroblast growth factor 17
Human Gene Id8822
Human Swiss Prot NoO60258
Mouse Swiss Prot NoP63075
SpecificityFGF-17 Polyclonal Antibody detects endogenous levels of FGF-17 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF17; Fibroblast growth factor 17; FGF-17
Observed Band(KD)25
Functiondevelopmental stage:Detected in embryos at E14.5, but not at E10.5 and E19.5. Preferentially expressed in the neuroepithelia of the isthmus and septum of the embryonic brain at E14.5.,function:May be a signaling molecule in the induction and patterning of the embryonic brain.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Preferentially expressed in the embryonic brain.,
Subcellular Locationextracellular region,extracellular space,intracellular,
ExpressionFetal brain,
Backgroundfibroblast growth factor 17(FGF17) Homo sapiens This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],