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Cell Signal Transduction Research Antibodies
M-CSF Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight60119Da
Protein NameMacrophage colony-stimulating factor 1
Human Gene Id1435
Human Swiss Prot NoP09603
Mouse Swiss Prot NoP07141
SpecificityM-CSF Polyclonal Antibody detects endogenous levels of M-CSF protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCSF1; Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim
Observed Band(KD)48
Functionfunction:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.,PTM:Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.,PTM:Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.,subunit:Homodimer or heterodimer; disulfide-linked.,
Subcellular Locationextracellular space,plasma membrane,membrane,integral component of membrane,perinuclear region of cytoplasm,extracellular exosome,CSF1-CSF1R complex,
ExpressionEndometrium,Kidney,Pancreatic carcinoma,T lymphoblast,Trophoblast,Urine,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human CSF1. AA range:505-554
Gene NameCSF1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundcolony stimulating factor 1(CSF1) Homo sapiens The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-75553-Conjugate. Price: $485 / Size: 100μl.
E20-75553-FITC$485 / 100μlE20-75553-Biotin$485 / 100μlE20-75553-HRP$485 / 100μlE20-75553-AP$485 / 100μlE20-75553-AF350$485 / 100μlE20-75553-AF405M$485 / 100μlE20-75553-AF488$485 / 100μlE20-75553-AF514$485 / 100μlE20-75553-AF532$485 / 100μlE20-75553-AF555$485 / 100μlE20-75553-AF568$485 / 100μlE20-75553-AF405S$485 / 100μlE20-75553-AF405L$485 / 100μlE20-75553-AF546$485 / 100μlE20-75553-AF594$485 / 100μlE20-75553-AF610$485 / 100μlE20-75553-AF635$485 / 100μlE20-75553-AF647$485 / 100μlE20-75553-AF680$485 / 100μlE20-75553-AF700$485 / 100μlE20-75553-AF750$485 / 100μlE20-75553-AF790$485 / 100μlE20-75553-APC$485 / 100μlE20-75553-PE$485 / 100μlE20-75553-Cy3$485 / 100μlE20-75553-Cy5$485 / 100μlE20-75553-Cy5.5$485 / 100μlE20-75553-Cy7$485 / 100μlE20-75553-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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