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Cell Signal Transduction Research Antibodies

PSA Polyclonal Antibody

E20-75551Cite ID: EN0055684DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight28741Da
Protein NameProstate-specific antigen
Human Gene Id354
Human Swiss Prot NoP07288
SpecificityPSA Polyclonal Antibody detects endogenous levels of PSA protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
Observed Band(KD)29
Functioncatalytic activity:Preferential cleavage: -Tyr-|-Xaa-.,function:Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.,online information:Prostate-specific antigen entry,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,
Subcellular Locationextracellular region,extracellular space,nucleus,protein complex,extracellular exosome,
ExpressionLeukocyte,PNS,Prostate,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human KLK3. AA range:131-180
Gene NameKLK3
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundkallikrein related peptidase 3(KLK3) Homo sapiens Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75551-Conjugate. Price: $485 / Size: 100μl.

E20-75551-FITC$485 / 100μlE20-75551-Biotin$485 / 100μlE20-75551-HRP$485 / 100μlE20-75551-AP$485 / 100μlE20-75551-AF350$485 / 100μlE20-75551-AF405M$485 / 100μlE20-75551-AF488$485 / 100μlE20-75551-AF514$485 / 100μlE20-75551-AF532$485 / 100μlE20-75551-AF555$485 / 100μlE20-75551-AF568$485 / 100μlE20-75551-AF405S$485 / 100μlE20-75551-AF405L$485 / 100μlE20-75551-AF546$485 / 100μlE20-75551-AF594$485 / 100μlE20-75551-AF610$485 / 100μlE20-75551-AF635$485 / 100μlE20-75551-AF647$485 / 100μlE20-75551-AF680$485 / 100μlE20-75551-AF700$485 / 100μlE20-75551-AF750$485 / 100μlE20-75551-AF790$485 / 100μlE20-75551-APC$485 / 100μlE20-75551-PE$485 / 100μlE20-75551-Cy3$485 / 100μlE20-75551-Cy5$485 / 100μlE20-75551-Cy5.5$485 / 100μlE20-75551-Cy7$485 / 100μlE20-75551-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.