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Cell Signal Transduction Research Antibodies
FGF-2 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight17254Da
Protein NameFibroblast growth factor 2
Human Gene Id2247
Human Swiss Prot NoP09038
Mouse Gene Id14173
Mouse Swiss Prot NoP15655
Rat Gene Id54250
Rat Swiss Prot NoP13109
SpecificityFGF-2 Polyclonal Antibody detects endogenous levels of FGF-2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameFGF2; FGFB; Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2
Observed Band(KD)30
Functionfunction:The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.,miscellaneous:This protein binds heparin more strongly than does aFGF.,PTM:Several N-termini starting at positions 48, 54, 47 and 65 have been identified by direct sequencing.,sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.,similarity:Belongs to the heparin-binding growth factors family.,subunit:Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2.,tissue specificity:Expressed in granulosa and cumulus cells.,
Subcellular Locationextracellular region,extracellular space,nucleus,cytoplasm,
ExpressionBlood,Hepatoma,Placenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FGF2. AA range:151-200
Gene NameFGF2
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundfibroblast growth factor 2(FGF2) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75549-Conjugate. Price: $485 / Size: 100μl.
E20-75549-FITC$485 / 100μlE20-75549-Biotin$485 / 100μlE20-75549-HRP$485 / 100μlE20-75549-AP$485 / 100μlE20-75549-AF350$485 / 100μlE20-75549-AF405M$485 / 100μlE20-75549-AF488$485 / 100μlE20-75549-AF514$485 / 100μlE20-75549-AF532$485 / 100μlE20-75549-AF555$485 / 100μlE20-75549-AF568$485 / 100μlE20-75549-AF405S$485 / 100μlE20-75549-AF405L$485 / 100μlE20-75549-AF546$485 / 100μlE20-75549-AF594$485 / 100μlE20-75549-AF610$485 / 100μlE20-75549-AF635$485 / 100μlE20-75549-AF647$485 / 100μlE20-75549-AF680$485 / 100μlE20-75549-AF700$485 / 100μlE20-75549-AF750$485 / 100μlE20-75549-AF790$485 / 100μlE20-75549-APC$485 / 100μlE20-75549-PE$485 / 100μlE20-75549-Cy3$485 / 100μlE20-75549-Cy5$485 / 100μlE20-75549-Cy5.5$485 / 100μlE20-75549-Cy7$485 / 100μlE20-75549-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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