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Cell Signal Transduction Research Antibodies
MyoD Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight34490Da
Protein NameMyoblast determination protein 1
Human Gene Id4654
Human Swiss Prot NoP15172
Mouse Gene Id17927
Mouse Swiss Prot NoP10085
Rat Gene Id337868
Rat Swiss Prot NoQ02346
SpecificityMyoD Polyclonal Antibody detects endogenous levels of MyoD protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameMYOD1; BHLHC1; MYF3; MYOD; Myoblast determination protein 1; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3
Observed Band(KD)35
Functionfunction:Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.,online information:MyoD entry,PTM:Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function.,PTM:Ubiquitinated on the N-terminus; which is required for proteasomal degradation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1.,
Subcellular Locationnuclear chromatin,nucleus,nucleoplasm,transcription factor complex,cytoplasm,myofibril,
ExpressionMuscle,Skeletal muscle,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MYOD1. AA range:91-140
Gene NameMYOD1
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundmyogenic differentiation 1(MYOD1) Homo sapiens This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-75545-Conjugate. Price: $485 / Size: 100μl.
E20-75545-FITC$485 / 100μlE20-75545-Biotin$485 / 100μlE20-75545-HRP$485 / 100μlE20-75545-AP$485 / 100μlE20-75545-AF350$485 / 100μlE20-75545-AF405M$485 / 100μlE20-75545-AF488$485 / 100μlE20-75545-AF514$485 / 100μlE20-75545-AF532$485 / 100μlE20-75545-AF555$485 / 100μlE20-75545-AF568$485 / 100μlE20-75545-AF405S$485 / 100μlE20-75545-AF405L$485 / 100μlE20-75545-AF546$485 / 100μlE20-75545-AF594$485 / 100μlE20-75545-AF610$485 / 100μlE20-75545-AF635$485 / 100μlE20-75545-AF647$485 / 100μlE20-75545-AF680$485 / 100μlE20-75545-AF700$485 / 100μlE20-75545-AF750$485 / 100μlE20-75545-AF790$485 / 100μlE20-75545-APC$485 / 100μlE20-75545-PE$485 / 100μlE20-75545-Cy3$485 / 100μlE20-75545-Cy5$485 / 100μlE20-75545-Cy5.5$485 / 100μlE20-75545-Cy7$485 / 100μlE20-75545-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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