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Cell Signal Transduction Research Antibodies

Ub Polyclonal Antibody

E20-75541Cite ID: EN0055674DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the N-terminal region of human Ub.
Gene NameUBA52/RPS27A/UBB/UBC
DilutionIF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Product Information

Protein NameUbiquitin
Human Swiss Prot NoP62987/P62979/P0CG47/P0CG48
SpecificityUb Polyclonal Antibody detects endogenous levels of Ub protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameUBB; Polyubiquitin-B; UBC; Polyubiquitin-C; RPS27A; UBA80; UBCEP1; Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; UBA52; UBCEP2; Ubiquitin-60S ribosomal protein L40; CEP52; Ubiquitin A-52 residue ribosomal protein fusion product 1
Observed Band(KD)80 50
Functionfunction:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair.,miscellaneous:This ribosomal protein is synthesized as a C-terminal extension protein (CEP) of ubiquitin.,miscellaneous:Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat, here in human a Val. Some ubiquitin genes contain a
Subcellular Locationextracellular space,nucleus,nucleoplasm,lysosomal membrane,cytosol,ribosome,plasma membrane,endosome membrane,cytosolic large ribosomal subunit,endocytic vesicle membrane,extracellular exosome,
ExpressionBrain,Epithelium,Fetal brain cortex,Liver,L
Backgroundubiquitin A-52 residue ribosomal protein fusion product 1(UBA52) Homo sapiens Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-75541-Conjugate. Price: $485 / Size: 100μl.

E20-75541-FITC$485 / 100μlE20-75541-Biotin$485 / 100μlE20-75541-HRP$485 / 100μlE20-75541-AP$485 / 100μlE20-75541-AF350$485 / 100μlE20-75541-AF405M$485 / 100μlE20-75541-AF488$485 / 100μlE20-75541-AF514$485 / 100μlE20-75541-AF532$485 / 100μlE20-75541-AF555$485 / 100μlE20-75541-AF568$485 / 100μlE20-75541-AF405S$485 / 100μlE20-75541-AF405L$485 / 100μlE20-75541-AF546$485 / 100μlE20-75541-AF594$485 / 100μlE20-75541-AF610$485 / 100μlE20-75541-AF635$485 / 100μlE20-75541-AF647$485 / 100μlE20-75541-AF680$485 / 100μlE20-75541-AF700$485 / 100μlE20-75541-AF750$485 / 100μlE20-75541-AF790$485 / 100μlE20-75541-APC$485 / 100μlE20-75541-PE$485 / 100μlE20-75541-Cy3$485 / 100μlE20-75541-Cy5$485 / 100μlE20-75541-Cy5.5$485 / 100μlE20-75541-Cy7$485 / 100μlE20-75541-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.