PI 3-Kinase p110δ Polyclonal Antibody

Name: PI 3-Kinase p110δ Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75537
Price: 225 USD
Availability: InStock

E20-75537Cite ID: EN0055670Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight119479Da

Protein NamePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Human Gene Id5293

Human Swiss Prot NoO00329

Mouse Gene Id18707

Mouse Swiss Prot NoO35904

SpecificityPI 3-Kinase p110δ Polyclonal Antibody detects endogenous levels of PI 3-Kinase p110δ protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NamePIK3CD; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta

Observed Band(KD)120

Functioncatalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.,pathway:Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.,PTM:Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Interacts with ERAS.,tissue specificity:Expressed predominantly in leukocytes.,

Subcellular Locationintracellular,cytosol,plasma membrane,phosphatidylinositol 3-kinase complex,mast cell granule,

ExpressionBrain,Clones donated by RIKEN,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human PIK3CD. AA range:41-90

Gene NamePIK3CD

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.

Backgroundphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta(PIK3CD) Homo sapiens Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75537-Conjugate. Price: $485 / Size: 100μl.

E20-75537-FITC$485 / 100μlE20-75537-Biotin$485 / 100μlE20-75537-HRP$485 / 100μlE20-75537-AP$485 / 100μlE20-75537-AF350$485 / 100μlE20-75537-AF405M$485 / 100μlE20-75537-AF488$485 / 100μlE20-75537-AF514$485 / 100μlE20-75537-AF532$485 / 100μlE20-75537-AF555$485 / 100μlE20-75537-AF568$485 / 100μlE20-75537-AF405S$485 / 100μlE20-75537-AF405L$485 / 100μlE20-75537-AF546$485 / 100μlE20-75537-AF594$485 / 100μlE20-75537-AF610$485 / 100μlE20-75537-AF635$485 / 100μlE20-75537-AF647$485 / 100μlE20-75537-AF680$485 / 100μlE20-75537-AF700$485 / 100μlE20-75537-AF750$485 / 100μlE20-75537-AF790$485 / 100μlE20-75537-APC$485 / 100μlE20-75537-PE$485 / 100μlE20-75537-Cy3$485 / 100μlE20-75537-Cy5$485 / 100μlE20-75537-Cy5.5$485 / 100μlE20-75537-Cy7$485 / 100μlE20-75537-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.