OAS2 Polyclonal Antibody

Name: OAS2 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-75536
Price: 225 USD
Availability: InStock

E20-75536Cite ID: EN0055669Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight82431Da

Protein Name2'-5'-oligoadenylate synthase 2

Human Gene Id4939

Human Swiss Prot NoP29728

Mouse Gene Id246728

Mouse Swiss Prot NoE9Q9A9

Rat Gene Id363938

Rat Swiss Prot NoQ5MYU0

SpecificityOAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameOAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS

Observed Band(KD)82

Functioncatalytic activity:Binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs.,function:May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,subcellular location:Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.,subunit:Homodimer.,

Subcellular Locationnucleus,cytoplasm,mitochondrion,endoplasmic reticulum,cytosol,membrane,intracellular membrane-bounded organelle,perinuclear region of cytoplasm,

ExpressionBlood,Colon,Testis,Uterus,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110

Gene NameOAS2

DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.

Background2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-75536-Conjugate. Price: $485 / Size: 100μl.

E20-75536-FITC$485 / 100μlE20-75536-Biotin$485 / 100μlE20-75536-HRP$485 / 100μlE20-75536-AP$485 / 100μlE20-75536-AF350$485 / 100μlE20-75536-AF405M$485 / 100μlE20-75536-AF488$485 / 100μlE20-75536-AF514$485 / 100μlE20-75536-AF532$485 / 100μlE20-75536-AF555$485 / 100μlE20-75536-AF568$485 / 100μlE20-75536-AF405S$485 / 100μlE20-75536-AF405L$485 / 100μlE20-75536-AF546$485 / 100μlE20-75536-AF594$485 / 100μlE20-75536-AF610$485 / 100μlE20-75536-AF635$485 / 100μlE20-75536-AF647$485 / 100μlE20-75536-AF680$485 / 100μlE20-75536-AF700$485 / 100μlE20-75536-AF750$485 / 100μlE20-75536-AF790$485 / 100μlE20-75536-APC$485 / 100μlE20-75536-PE$485 / 100μlE20-75536-Cy3$485 / 100μlE20-75536-Cy5$485 / 100μlE20-75536-Cy5.5$485 / 100μlE20-75536-Cy7$485 / 100μlE20-75536-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.